Assisted reproductive technology: an uncommon, but increasing, cause of parent-child ABO discrepancy

In the course of evaluating an infant with mild ABO hemolytic disease of the fetus or newborn, we detected an unexpected discrepancy between the mother’s group O phenotype and the infant’s group AB phenotype. While we were considering the possibilities of a blood sample or patient misidentification, cis-AB or Bombay phenotype, we learned that the mother had attended a fertility clinic and her pregnancy was induced using a donor egg (oocyte). The newborn’s total bilirubin peaked at 5 mg/dL and returned to a normal concentra-tion with phototherapy. Mother and child were dis-charged uneventfully 48 hours after the delivery (read more)